The well-being of guests is top of mind at Choice-branded hotels. Guests may experience a variety of new, improved cleanliness protocols and products. Rest and refresh at the smoke-free Comfort Inn US Hwy 80 hotel in Demopolis, AL. We are near the Demopolis Historic Business District, Demopolis Lake, Bluff Hall, Foscue Park, Gaineswood, and Black Warrior and Tombigbee Rives. Amenities include free WiFi, free ample parking, free hot breakfast, meeting room, business and fitness centers. Behind every great day is a great night in your guest room, which features a refrigerator, microwave, coffee maker, hair dryer, HDTV, iron and ironing board. Some rooms also have a wet bar. Also, earn rewards including free nights and gift cards with our Choice Privileges Rewards program. No Pets.