Emergency Center - CHI St. Luke's Health - Huntsville, TX is dedicated to delivering high quality, compassionate care to Huntsville, TX and nearby communities. Visit us at 540 Interstate 45 S or call (936) 755-5288 for more information. Our Huntsville emergency room offers care for both children and adults with minor and major injuries or illnesses without the long wait at a hospital emergency department. As a hospital-backed emergency room, patients can expect to have access to on-call CHI St. Luke’s Health specialists and seamless admission to a CHI St. Luke’s Health Hospital when necessary.