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The Hampton Inn I-70 Columbia hotel is conveniently located at Exit 128A, off Missouri Interstate 70 at the intersection of Highway 63, and is central to everything Columbia has to offer. The University of Missouri, downtown Columbia, Columbia Regional Airport, and Columbia Regional Hospital are all just minutes from the hotel. Other area attractions near our Columbia I-70 Hampton Inn include the Boone County Fairgrounds, Columbia Mall, Finger Lakes State Park, art galleries, museums and nature and fitness trails. Enjoy free breakfast daily and free WiFi.