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The Hampton Inn Grand Island hotel in Nebraska is located north of I-80 off Hwy. 281 on Diers Avenue. The Hampton Inn Grand Island hotel is centrally located near businesses in Grand Island and the Conestoga Mall which is minutes away. For dining there are tremendous restaurants; Whiskey Creek Steakhouse, Nonna's Italian Restaurant, The Chicken Coop, Farmers Daughter and many more. For the explorers the Stuhr Museum is only three miles south. There are also numerous activities in the Grand Island surrounding area. There are three room types to choose from; two queen beds, one king bed or our beautiful whirlpool suites with either a king or two queen beds.