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The Hampton Inn Johnson City hotel is located southwest of downtown Johnson City, Tennessee, across from Johnson City Medical Center and East Tennessee State University. This beautifully landscaped hotel is nestled between the Blue Ridge Mountains and close to the heart of the strongest growth corridor of Johnson City. The Hampton Inn hotel in Johnson City, Tennessee is easily accessible by Interstate 26 and Highway 11E. The newest shopping arena, The Crossings, is two miles from the hotel, along with restaurants featuring both local and nationally known cuisine. The Hampton Inn Johnson City hotel is just 15 minutes away from the Tri-Cities Regional Airport.