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The Hilton Garden Inn Anderson hotel is in beautiful upstate South Carolina, conveniently located off Interstate 85 at Exit 19A. Adjacent to Lake Hartwell, our hotel is only 13 miles from Clemson University and just minutes from Anderson University and Tri County Technical College. Our hotel offers easy accesses to the city's business and manufacturing district, shopping, dining and entertainment venues as well as historic downtown. Anderson, South Carolina is just two hours from Atlanta, Georgia and Charlotte, North Carolina and just minutes from Greenville-Spartanburg International Airport (GSP).