Jamestown Regional Medical Center is a 25 bed, state of the art facility located in the South Central region of North Dakota. JRMC is located at 2422 20th St SW Jamestown ND 58401 I94 Exit 256 South. Jamestown Hospital was built in 1929. In July of 2011 Jamestown Hospital moved to a new location and changed their name to Jamestown Regional Medical Center. JRMC is a critical access hospital serving over 55,000 people in a nine county region.