Dr. Manzi is currently Professor of Medicine and Chair of the Medicine Institute at Allegheny Health Network, Pittsburgh, PA. Dr. Manzi received her MD from the University of Pittsburgh School of Medicine. She completed her medical Internship and Residency at Duke University Medical Center, after which she completed her Fellowship in Rheumatology at UPMC, and received her Masters of Public Health (MPH) from the University of Pittsburgh Graduate School of Public Health. Dr. Manzi is recognized internationally as a pioneer in the investigation of premature cardiovascular disease in systemic lupus erythematosus and in the discovery of biomarkers for lupus diagnosis, monitoring and stratification. She has published over 200 scientific reports and book chapters and is inventor of the cell-bound complement activation products (CB- CAPs) technology platform for which she holds more than 20 patents. Her research program has received multi-million dollar support from many organizations including the NIH, the Department of Defense, the Lupus Foundation of America and the Arthritis Foundation. Dr. Manzi has served on Advisory Boards for the Food and Drug Administration and more than 20 pharmaceutical and biotech companies and has chaired or served on numerous NIH study sections and data safety monitoring boards. She has served as Medical Director and is currently Chair of the Board of Directors of the Lupus Foundation of America. Dr. Manzi has mentored more than 100 undergraduate, graduate, and medical students, postdoctoral fellows and junior faculty.